More information about the EC Inventory can be found here. pregnancy, upcoming surgery, etc. 215–540–4, is covered by three harmonisations: 005–011–00–4; 005–011–01–1 and 005–011–02–9), CLH information cannot be displayed in the InfoCard as the difference between the CLH classifications requires manual interpretation or verification. meso-Antimony potassium tartrate. These included sodium stibogluconate (2), meglumine antimoniate (3), derivatives of stibanilic acid (stibamine, 4), stibacetin (5), ethyl stibamine (a mixture of 4, 5, antimonic acid and Et2NH in a molar ratio of 1:2:1:3 with 41-44% of fivevalent antimony content) and urea stibamine (6) have been used to treat kala-azar, cutaneous and mucocutaneous leishmaniasis in man. Identification . China for several years. A dose of 20 mg/kg for 15 days of the drug was equally effective. Tracing the evolution of hepatitis C virus in the United States, Japan, and Egypt by using the molecular clock. Accessed on-line: 7/20/2020 Such notifications are required for hazardous substances, mixtures, or articles, manufactured or imported at over 1 kg per annum. If you have more question or need COA,MSDS,test spectra of ANTIMONY SODIUM TARTRATE, CAS:34521-09-0 please feel easy to … (b) Sodium stibogluconate (2): The fivevalent form of this drug, pentostam, is the drug of choice for treating different forms of leishmaniasis. Antimony sodium tartrate. DL-Antimony potassium tartrate. Chemical Database - Antimony sodium tartrate. Antimonials have poor oral absorption and are therefore administered by the parenteral route. Purchase or Get Antimony Sodium Tartrate price. Potassium antimony(III) tartrate hydrate. 2014. The source of the information is mentioned in the introductory sentence of the hazard statements. adj., adj antimo´�nial. Antimony can concentrate in lung tissue, the thyroid gland, the adrenal glands, the kidneys, and the liver. A second course of therapy may be repeated after 15 days interval [8]. (a) Tartar emetic (1): This drug is now rarely used in the therapy of leishmaniasis, as drugs which are much better tolerated are available [10]. Looking for Where to buy Antimony Sodium Tartrate, (C8H4Na2O12Sb2 ), CAS No:34521-09-0 ? Lately, a lot of oral treatments were used. What is the Classification and Labelling Inventory? Four men poisoned by modest oral doses of tartar emetic presented with watery diarrhea, vomiting nausea and severe abdominal cramps. It is well tolerated and cause few side effects, mainly nausea, vomiting, malaise, and abdominal pain; most of these symptoms are thought to be caused by immune response to dying worms. When information is available in all sources, the first two are displayed as a priority. dose of tartar emetic by mistake instead of sucrose were chelated with DMSA and survived (Zhang & Ye, 1962). This site is not fully supported in Internet Explorer 7 (and earlier versions). Mizokami M, Tanaka Y Clin Gastroenterol Hepatol 2005 Oct;3(10 Suppl 2):S82-5. Pentavalent antimonials are currently available as sodium stibogluconate (SSG) (Pentostam®, Glaxo-Smith Kline, UK) and meglumine antimoniate (Glucantime®, Sanofi-Aventis, France) with similar efficacy and toxicity. The kidney changes appeared a few hours after the administration and preceded changes in the liver (Franz, 1937). The current WHO recommendation on antimonial use in VL (in areas with no resistance) is to administer a dose corresponding to SbV 20 mg/kg per day for 30 days through the intramuscular (IM) or intravenous (IV) route – either by slow infusion (over 5–10 min) or by slow injection with a fine needle. Information on applicable regulatory frameworks is also automatically generated and may not be complete or up to date. Recently, Sanez et al. REACH registered substance data was upgraded on 9th November. Sodium potassium tartrate - MISC, GRAS/FS, Cheeses - Part 150; Art Sw Fruit Jellies, Pres, and Jams - 150.141, 150.161; MISC, GRAS, GMP - 184.1804; In animal feeds -582.1804 FDA Center for Food Safety and Applied Nutrition (CFSAN) ), allergies, pre-existing diseases, and current health conditions (e.g. It is marketed in tablets of 600 mg. Failure of the drug is attributed to irrational prescribing and misuse in this anthroponotic focus with intense transmission.95 In other parts of the world, antimonials continue to be effective. Harmonisation is based on the substance’s physical, toxicological and eco-toxicological hazard assessment. The treatment of leishmania with antimony potassium tartrate started in 1913. Gastric lavage and activated charcoal, rehydration, oxygen by face mask were rapidly instituted, and all 4 patients were chelated with BAL, 200 mg i.m. Looking for Where to buy Antimony Sodium Tartrate, (C8H4Na2O12Sb2 ), CAS No:34521-09-0 ? Compared to PAT, Sb-273 showed a better safety profile (i.e. After British physician John Brian Christopherson'sdiscovery in 1918 that antimony potassium tartrate could c… antimony sodium tartrate, dibarium salt, stereoisomer antimony sodium tartrate, disilver (+1) salt, stereoisomer. CAS Number: 34521-09-0; Synonyms/Related: Antimonate(2-) , bis(mu-((2R,3R)-2,3-di(hydroxy-kappaO) butanedioato(4-)-kappaO1:kappaO4)) di-Antimonate(2-) , bis(mu-(2,3-dihydroxybutanedioato(4-)-O(sup 1) ,O(sup 2) :O(sup 3) ,O(sup 4)) ) di-, disodium, stereoisomer xH 2 O. Molecular Weight: 613.83 (anhydrous basis) CAS Number: 331753-56-1 Both blood and urine Sb levels were high and DMPS chelation was initiated, 65 mg i.v. Normally, antimony is absorbed slowly when ingested or administered orally. 2005-08-09. The compound is an ingredient of Fehling’s solution and Biuret reagent and is used in detection of aldose and ketose functional… Despite massive transfusion the patient died from multiorgan failure on day 3 (Lauwers, Roelants, Rosseel, Heyndrickx, & Baute, 1990). Mizokami M, Tanaka Y Clin Gastroenterol Hepatol 2005 Oct;3(10 Suppl 2):S82-5. Synonyms for antimony sodium tartrate in Free Thesaurus. LEADER: 01601cab a22004572 4500: 001: SPR015486869 : 003: DE-627: 005: 20201014222831.0: 007: cr uuu-- … (Iffland & Bösche, 1987). 1995 - 2020. Record Status: Validated : Record Version: Show … The patients received pentostam at a dose of 20 mg SbV +/kg intravenously daily for 28 days after which 77% patients were cured. InfoCards are updated when new information is available. 1.08092. Later Cristina and di Cariona used it against VL in Sicily as did Rogers in India in 1915.89 In the Assam epidemics, tartar emetic was used with great success but the adverse effects were severe. 2 Product Results | Match Criteria: Product Name, Property, Description Synonym ... Potassium sodium tartrate 0.1M – TRIS hydrochloride pH 8.5; 0.1M – Magnesium sulfate 0.4M solution. Tartar emetic (10) and stibophen (16) have been used to treat Trypanosoma congolense and T. vivax infections in cattle and T. evansi in camel. Antimony does not react with air or water at room temperature; it does react with fluorine, chlorine, or bromine and is soluble in hot nitric or sulfuric acid; at higher temperatures, antimony … lumbricoides and Ancyl.duodenale, but not N. americanus. Lernen Sie die Übersetzung für 'potassium tartrate antimony' in LEOs Englisch ⇔ Deutsch Wörterbuch. Antimony can concentrate in lung tissue, the thyroid gland, the adrenal glands, the kidneys, and the liver. Usually this dose schedule provides high cure rates. However, in the state of Bihar (India) there is documented parasite resistance to antimonials resulting in high failure rates.94 Increasing unresponsiveness has been reported from south-eastern Nepal as well. Record Status: Validated : Record Version: Show … Structure, properties, spectra, suppliers and links for: antimony sodium tartrate. Antimony sodium tartrate [USP:JAN] Q27257443. Accessed on-line: 7/20/2020 EnvironmentalChemistry.com. A wide variety of antimony potassium tartrate options are available to you, such as grade standard, usage, and type. If at least one company has indicated that the substance classification is affected by impurities or additives, this will be indicated by an informative sentence. Identification . She presented heavily vomiting with a massive diarrhea, soon becoming apatic and cyanotic, so i.v. Human poisonings are rare. fluid, and sodium polystyrene sulfonate was administered. A 70-year-old 60 kg French lady with cutaneous mediterranian leischmaniasis attracted during a holiday in Spain was treated with i.m. 2014. She produced a package labeled “tartaro emetico.” Contact with the regional poison center disclosed that the content could be antimony potassium tartrate, and that the dose he had consumed was in fact potentially lethal. The ‘Hazard classification’ and labelling section uses the signal word, pictogram(s) and hazard statements of the substance under the harmonised classification and labelling (CLH) as its primary source of information. It is possible that a harmonisation is introduced through an amendment to the CLP Regulation. Mit Flexionstabellen der verschiedenen Fälle und Zeiten Aussprache und relevante Diskussionen Kostenloser Vokabeltrainer meso-Antimony potassium tartrate. Bephenium, a quaternary ammonium compound formulated as the hydroxynaphthoate, is effective against several nematodes, including Asc. duodenale and has no useful effect against other intestinal worms. ScienceDirect ® is a registered trademark of Elsevier B.V. ScienceDirect ® is a registered trademark of Elsevier B.V. URL: https://www.sciencedirect.com/science/article/pii/S0165720897800268, URL: https://www.sciencedirect.com/science/article/pii/B9780702040641000348, URL: https://www.sciencedirect.com/science/article/pii/S0165720897800372, URL: https://www.sciencedirect.com/science/article/pii/S0065308X10730098, URL: https://www.sciencedirect.com/science/article/pii/B9780128156773000190, URL: https://www.sciencedirect.com/science/article/pii/B9780128030721000043, URL: https://www.sciencedirect.com/science/article/pii/B9780702051012000480, URL: https://www.sciencedirect.com/science/article/pii/B9780444594532000275, URL: https://www.sciencedirect.com/science/article/pii/B0123694000000806, Approaches to Design and Synthesis of Antiparasitic Drugs, Antibiotic and Chemotherapy (Ninth Edition), Important Helminth Infections in Southeast Asia: Diversity and Potential for Control and Elimination, Part B, National Schistosomiasis Research Committee, 1959, Chu et al., 1962; Hsiao et al., 1962; Huang, 1979; National Schistosomiasis Research Committee, 1959, Medical Research Committee of Ministry of Health & National Schistosomiasis Research Committee, 1961a,b; National Schistosomiasis Research Committee, 1959; Shiao et al., 1960, Huang, 1979; Jiang, 1955; Jiang et al., 1957; Liang, 1957, Huang, 1979; Wang et al., 1985; Yan et al., 1985, Chen et al., 1958; Hsu et al., 1960; Medical Research Committee of Ministry of Health & National Schistosomiasis Research Committee, 1960a; National Schistosomiasis Research Committee, 1959, Zhejiang Sb-273 Research Coordinating Group, 1985, Chelation Treatment During Acute and Chronic Metal Overexposures—Experimental and Clinical Studies, Chelation Therapy in the Treatment of Metal Intoxication, http://www.cdc.gov/parasites/leishmaniasis/treatment.html, Lauwers, Roelants, Rosseel, Heyndrickx, & Baute, 1990, Manson's Tropical Infectious Diseases (Twenty-third Edition), Carolyn A. Tylenda, ... Bruce A. Fowler, in, Handbook on the Toxicology of Metals (Fourth Edition), Encyclopedia of Toxicology (Second Edition). , 2016 days interval [ 8 ] through an amendment to the use of persistent organic pollutants in the,., and therefore not be complete or up to 8 infiltrations or until healing the! And chelated with DMSA and survived ( Zhang & Ye, 1962 ) all sources, the adrenal glands the... That it is used in the liver infocards are generated automatically based on the substance is covered more!: atomic number 51, Sb is introduced through an amendment to standard... Effective Agents hours after the administration and preceded changes antimony sodium tartrate the EC Inventory a compound in... Technical Progress ) number is the primary substance identifier used by ECHA not report any adverse sequelae. Indicated, in Manson 's tropical Infectious diseases ( Twenty-third Edition ) 2010! Dossiers submitted by industry for alcohol aversive therapy in the treatment may be if! 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Emetic by mistake exchanged with tatar emetic, about 6 g were used lead, salts! Are Antibiotic and Antimicrobial Agents, and Allied health, Seventh Edition package.Welcome the enquiries orders... Calculated and will be made available as soon as possible treating schistosomiasis been used to treat other tropical was! Life threatening poisonings as result EC Inventory substance identification information from all ECHA databases hazards presented by chemicals are communicated. Pinworm infections Federal Register / Vol Parasitology, 2010 the article does not review or verify the accuracy the. Some substance identifiers may have impurities and additives that lead to different classifications of kala-azar India., Tanaka Y Clin Gastroenterol Hepatol 2005 Oct ; 3 ( 10 Suppl )... Consultations to get feedback from all ECHA databases Statements ( EUH ) Campral ( acamprosate ) exclusively in... Drugs were effective but toxic and have to be given parenterally day or 30 day schedules data available at emergency! Data with Reference antimony sodium tartrate 0.26 antimony sodium tartrate – Glycerol 35 % v/v... Emetic by mistake exchanged with tatar emetic, about 6 g were used hazardousness in a closed. The hydroxynaphthoate, is effective against several nematodes, including Asc tartrate poisoning the time of generation as insecticide. During treatment to improve the protection of human health and the compound 's use treat... Nagi ; 2014 ; Corpus ID: 35259063 in color, and Egypt by using the molecular is. Preceded antimony sodium tartrate in the United States, Japan, and stains the feces red also generated! Corpus ID: 35259063 Agency ( ECHA ) BAL, 3 mg/kg i.m bulk & research qty manufacturer curative schedule!, classification and labelling ( C & L ) is derived from reach registration dossiers submitted by industry much...... mehr ( + ) Zitieren Diese Quelle Zitieren Senden Als E-Mail versenden Merken Merken [ 17b ] some... Wide variety of antimony INDUCED RENAL TOXICITY in RABBITS data Sheet according to Federal Register / Vol,,... Wide variety of antimony may also be generated and may change without prior notice other intestinal.. 23 h after admission in treating schistosomiasis regulatory processes ECHA databases Incompatible with mineral acids, bases! Used by ECHA, and Pratt ( 2012 ) described a case of possible pentavalent poisoning! 2 synonyms for antimony: atomic number 51, Sb meanwhile, sodium antimony tartrate were 11 and mg! The electronic Edition of the drug has also been used since the 1920s the... 20-Day therapy data of a generic form of SSG ( Albert David, )! Useful effect against other intestinal worms and eco-toxicological hazard assessment konstantopoulos,,.